Task-specific Ionic Liquid Promoted One-pot Robinson Annelation

KANG Liqin; LIAO Huiying; GUO Xiong

doi:10.3969/j.issn.2096-3424.2020.04.005

KANG Liqin, LIAO Huiying, GUO Xiong. Task-specific Ionic Liquid Promoted One-pot Robinson Annelation[J]. Journal of Technology, 2020, 20(4): 334-338. DOI: 10.3969/j.issn.2096-3424.2020.04.005

Citation:

KANG Liqin, LIAO Huiying, GUO Xiong. Task-specific Ionic Liquid Promoted One-pot Robinson Annelation[J]. Journal of Technology, 2020, 20(4): 334-338. DOI: 10.3969/j.issn.2096-3424.2020.04.005

Citation:

KANG Liqin, LIAO Huiying, GUO Xiong. Task-specific Ionic Liquid Promoted One-pot Robinson Annelation[J]. Journal of Technology, 2020, 20(4): 334-338. DOI: 10.3969/j.issn.2096-3424.2020.04.005

Task-specific Ionic Liquid Promoted One-pot Robinson Annelation

Graphical Abstract

Graphical Abstract

Abstract

Abstract

6-ethoxycarbonyl-3-phenyl-5-(4-chloro)phenyl-2-cyclohexenone could be synthesized through one-pot Robinson annelation from ethyl acetoacetate with 3-(4-chloropheny)-1-phenyl-2-en-1-one in good yield catalyzed by task-specific ionic liquid, 1-ethyl-3-methyl imidazole hydroxyl (emim OH). This process wass simple, high yield, environmentally benign and the catalyst could be recycled. The possible reaction scheme was studied.